[Heart failure in hypertensive patients with left ventricular hypertrophy]

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M A Ghanem Wisam1, P Mikes, J Bulas

  • 1I. interná klinika Lekárskej fakulty UK a Fakultná nemocnica, Bratislava.

Vnitrni Lekarstvi
|August 10, 2001
PubMed

Insights

Left ventricular hypertrophy (LVH) in hypertensive patients is linked to increased heart failure, diastolic dysfunction, and atrial fibrillation. This finding highlights LVH as a critical indicator of cardiovascular complications in hypertension.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Echocardiography

Background:

  • Left ventricular hypertrophy (LVH) is a recognized indicator of cardiovascular complications in hypertensive individuals.
  • Understanding the prevalence and impact of LVH is crucial for managing hypertension-related heart disease.

Purpose of the Study:

  • To compare the incidence of heart failure, left ventricular diastolic dysfunction, and chronic atrial fibrillation in hypertensive patients with and without LVH.
  • To assess the association between LVH and cardiac function parameters like ejection fraction.

Main Methods:

  • Retrospective analysis of hospital records for 192 hypertensive patients treated between 1996-1999.
  • Echocardiography (Penn convention) was used to define LVH based on left ventricular mass index.
  • Patients were matched for demographic parameters, hyperlipidemia, and smoking habits.

Main Results:

  • LVH was present in 128 patients and absent in 64, with no significant demographic differences between groups.
  • LVH-positive patients showed significantly higher rates of heart failure, diastolic dysfunction, and atrial fibrillation.
  • Ejection fraction was significantly lower in LVH-positive patients (50.3% vs. 56.5%).

Conclusions:

  • Left ventricular hypertrophy in hypertensive patients is associated with a more complicated disease course.
  • LVH significantly contributes to the development of chronic heart failure in hypertensive individuals.
  • Echocardiographic detection of LVH is vital for risk stratification and management of hypertensive patients.

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