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Dendritic cells and their role in skin-induced immune responses
Z Holíková1, J Hercogová, J Pizák
1Center of Cell Therapy and Tissue Repair, 2nd Faculty of Medicine, Charles University, Prague 5, Czech Republic. holikovazuzana@hotmail.com
Abstract:
This artide gives a brief review on dendritic cells (DC) with regard to their origin, life cyde and functions. The regulation of immune responses by DC functioning as antigen-presenting cells is discussed. Special attention is given to epidermal DC, e.g. Langerhans cells. The perspectives of DC-based therapy are also mentioned.