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Updated: Aug 1, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Merkel cell carcinoma: a rare cause of hypervascular nasal tumor
L Azizi1, K Marsot-Dupuch, P Bigel
1Department of Radiology, Hôpital Saint Antoine, 18 Rue du Faubourg Saint Antoine, 75012 Paris, France.
Abstract:
Cutaneous neuroendocrine carcinoma, first described in 1972, is an aggressive disease usually occurring in sun-exposed skin. Other sites have been described, however; such tumors occasionally occur within the nasal fossa. A high rate of metastasis (>30%) explains the poor prognosis. Descriptions of the imaging features of these tumors, mainly located in cutaneous region, are rare. We therefore present the imaging features of two cases of Merkel cell carcinoma involving the sinonasal region, suggestive of a hypervascular tumor.
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