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Updated: Jul 31, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
Published on: March 17, 2010
The lock-in phase in the urotropine-sebacic acid system
M Gardon1, A Schönleber, G Chapuis
1Institut de Cristallographie, Université de Lausanne, BSP Dorigny, CH-1015 Lausanne, Switzerland.
Abstract:
The 1,10-decanedioic acid-1,3,5,7-tetraazatricyclo[3.3.1.1(3,7)]decane (1/1) system, C(10)H(18)O(4).C(6)H(12)N(4), was studied at 215 (2) K. Its analysis provides important information with regard to the long-standing acid-carboxylate controversy in the urotropine-alkanedioic acid system. In the present structure, all the chain end-groups display a clear acid character. The asymmetric unit of this commensurate modulated phase contains two molecules of diacid as well as two molecules of urotropine. Furthermore, the chain packing suggests a possible order parameter for the lock-in transition.
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