Related Experiment Video
Updated: Oct 5, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Five-year analysis of extrahospital consumption of betalactams in Spain]
M I Calvo Plaza1, R M Moreno Ubeda, V D Dominguez Rojas
1Dpto. de Medicina Preventiva, Salud Pública e Historia de la Ciencia, Universidad Complutense de Madrid.
Abstract:
We carried out a qualitative and quantitative study to determine extrahospital consumption of both broad-spectrum penicillins and cephalosporins in Spain in the period 1993-1997. Penicillins were the most consumed group, followed by macrolides and cephalosporins. Units and value (ptas.) of penicillins and cephalosporins during these five years show interannual variations. Nevertheless, monthly analysis of consumption for both groups showed a stable tendency, with peaks in winter months and drops in the summer. Both penicillins (54.38%) and cephalosporins (27.71%) were prescribed mainly for upper respiratory tract infections. Men received more penicillins and cephalosporins than women (51.02% and 55.09%). Children under 11 years were the main group for consumption of both types of antibiotic, while patients aged 55-64 years were the group with the least consumption.
Related Concept Videos
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Production of Antibiotics
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
Antimicrobial Effectiveness