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First-trimester ultrasound
1Department of Public Health, Erasmus University Rotterdam, Rotterdam, The Netherlands. snijders@generationr.nl
Clinics in Perinatology
|August 14, 2001
Summary
First-trimester fetal ultrasound, particularly nuchal translucency (NT) measurement, is increasingly used. Increased NT effectively screens for chromosomal anomalies and may signal other fetal health issues.
Area of Science:
- Maternal-Fetal Medicine
- Prenatal Diagnostics
- Medical Imaging
Background:
- First-trimester fetal ultrasound use is rising.
- Nuchal translucency (NT) measurement is a key component of early prenatal screening.
Purpose of the Study:
- To review the literature on first-trimester fetal ultrasound.
- To emphasize the role and accuracy of nuchal translucency (NT) measurements.
Main Methods:
- Literature review of published studies on first-trimester fetal ultrasound.
- Focus on studies detailing nuchal translucency (NT) measurement protocols and outcomes.
Main Results:
- Increased NT identifies approximately 80% of chromosomal anomalies.
- The false-positive rate for increased NT is approximately 5% when measured by established guidelines.
- Increased NT is associated with structural defects, genetic disorders, and twin-twin transfusion syndrome in monochorionic pregnancies.
Conclusions:
- Nuchal translucency (NT) measurement is a valuable screening tool in early pregnancy.
- Adherence to standardized guidelines is crucial for accurate NT assessment.
- Increased NT warrants further investigation for potential fetal abnormalities.