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Updated: Sep 9, 2026
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Prenatal diagnosis using fetal cells and free fetal DNA in maternal blood
1Department of Obstetrics and Gynecology, University of Basel, Basel, Switzerland. wholzgreve@uhbs.ch
Abstract:
The presence of fetal cells and free fetal DNA in maternal blood offers an exciting opportunity for the development of safe noninvasive forms of prenatal diagnosis. Research in this field has, however, also indicated that their levels in the maternal circulation are increased in certain pregnancy-related disorders, such as preeclampsia. Their closer examination may shed new light on the underlying etiology of this enigmatic disorder.
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