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Updated: Sep 21, 2026

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
Published on: October 10, 2011
Liver transplantation of hepatic stem cells: potential use for treating liver diseases
1Laboratoire de Biologie Cellulaire, INSERM U.327, CHU Bichat-Claude Bernard, Université Paris 7, France. u327@bichat.inserm.fr
Abstract:
Hepatic stem cells are an alternative means for repopulating the liver after various injuries instead of liver transplantation. The first step before use is to select stem cells that will be good candidates. This review discusses the different candidates including fetal progenitor bipotential hepatic stem cells; adult hepatocytes, which can be considered as unipotential committed stem cells; and oval cells, a type of nonparenchymal pluripotential hepatic stem cell. The advantages and disadvantages of each type of cell are discussed and several other possible alternatives, such as the use of hematopoietic stem cells are analyzed.
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