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Kikuchi-Fujimoto disease. A case report
M Vicente Barrero1, M R Knezevic, J J Castellano Reyes
1Servicio de Estomatología, Cirugía Oral y Maxilofacial, Hospital Insular, Las Palmas de Gran Canaria, España. mvicente@idecnet.com
Abstract:
Histologically, Kikuchi-Fujimoto disease (KFD) is a necrotising, self-limiting lymphadenitis. It typically affects the lymph nodes of the neck and it is often accompanied by a high fever. The present paper documents the case of a 28-year old male carrier of KFD. From the x-ray images, the KFD clinically appeared to be a submandibular salivary gland tumor. An ultrasound study led us to believe that it was more likely a branchial cyst. Malignant lymphoma can be mistaken for KFD, thus the diagnosis must be precise and the differentiation is crucial.
Insights
Kikuchi-Fujimoto disease (KFD) is a necrotizing lymphadenitis that can mimic other conditions. This case highlights the diagnostic challenges in differentiating KFD from tumors and cysts, emphasizing precise diagnosis.
Area of Science:
- Pathology
- Immunology
- Oncology
Background:
- Kikuchi-Fujimoto disease (KFD) is characterized as necrotizing, self-limiting lymphadenitis, typically affecting cervical lymph nodes and presenting with fever.
- Accurate differentiation of KFD from other conditions like malignant lymphoma is critical for appropriate patient management.
Observation:
- This report details a case of KFD in a 28-year-old male.
- Radiographic imaging suggested a submandibular salivary gland tumor, while ultrasound indicated a branchial cyst.
Findings:
- The clinical presentation of KFD mimicked a submandibular salivary gland tumor on X-ray and a branchial cyst on ultrasound.
- Histopathological examination is essential for confirming the diagnosis of KFD.
Implications:
- This case underscores the importance of considering KFD in the differential diagnosis of neck masses.
- Precise diagnostic methods are crucial to distinguish KFD from malignant lymphoma and other neoplastic or cystic lesions.
- Early and accurate diagnosis of KFD prevents misdiagnosis and ensures appropriate treatment strategies.
