Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diabetic capillaropathy.

R E Yodaiken, V Pardo

    Human Pathology
    |July 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Diabetic capillaropathy, a complication of diabetes mellitus, involves changes in capillary basal lamina thickness. Detecting early diabetes is currently impossible, but advanced stages show ultrastructural capillary changes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tuning Coherent-Phonon Heat Transport in LaCoO<sub>3</sub>/SrTiO<sub>3</sub> Superlattices.

    The journal of physical chemistry letters·2021
    Same author

    Single administration of recombinant IL-6 restores the gene expression of lipogenic enzymes in liver of fasting IL-6-deficient mice.

    British journal of pharmacology·2016
    Same author

    Electronic Degeneracy and Intrinsic Magnetic Properties of EpitaxialNb: SrTiO3 Thin Films Controlled by Defects.

    Physical review letters·2015
    Same author

    Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

    Cell death & disease·2014
    Same author

    Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge.

    Cell death & disease·2014
    Same author

    Magnetic field induced transition in vanadium spinels.

    Physical review letters·2014
    Same journal

    TRPS1 and GATA3 Expression in BRG1/SMARCA4-deficient Malignant Neoplasms.

    Human pathology·2026
    Same journal

    Clinicopathologic and Molecular Characteristics of Acral Melanomas Harboring RARA Fusions.

    Human pathology·2026
    Same journal

    Clinical Impact of Second Opinion Consultation in Bladder Biopsies and Transurethral Resection of Bladder Tumors.

    Human pathology·2026
    Same journal

    Prognostic relevance and molecular correlates of Claudin-1 expression in pancreatic neuroendocrine tumors.

    Human pathology·2026
    Same journal

    Mixed Phenotype Acute Leukemia: Lineage Assignment, Immunophenotypic Classification and Genetic Insights.

    Human pathology·2026
    Same journal

    Chronic myelomonocytic leukemia revisited: A comprehensive review with emphasis on the oligomonocytic subtype.

    Human pathology·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Pathology
    • Microcirculation

    Background:

    • Diabetic capillaropathy is a microvascular complication of diabetes mellitus.
    • Capillary basal lamina thickness can be influenced by aging, venous stasis, and environmental factors.
    • The precise contribution of diabetes mellitus to basal lamina thickening is not well-quantified due to confounding variables.

    Purpose of the Study:

    • To define and review diabetic capillaropathy.
    • To assess the feasibility of detecting early diabetes through capillary changes.
    • To explore the utility of peripheral capillary ultrastructure in diagnosing advanced diabetic capillaropathy.

    Main Methods:

    • Review of existing literature on diabetic capillaropathy.
    • Analysis of physiological and pathological factors affecting capillary basal lamina.

    Related Experiment Videos

  • Examination of peripheral capillary ultrastructure in late-stage diabetes.

    • Main Results:

    • Accurate measurement of diabetes-specific basal lamina thickening is hindered by confounding factors.
    • Early detection of diabetes via capillary basal lamina changes is currently not feasible.
    • Ultrastructural analysis of peripheral capillaries can reveal widespread capillaropathy in advanced diabetes.

    Conclusions:

    • Diabetic capillaropathy is a complex condition influenced by multiple factors.
    • Current methods are insufficient for early diabetes detection based on capillary changes.
    • Peripheral capillary ultrastructure serves as a diagnostic marker for advanced diabetic capillaropathy when clinical signs are ambiguous.