Esterase-D polymorphism in Assam by cellulose acetate electrophoresis

Area of Science:

• Biochemistry
• Population Genetics
• Human Genetics

Background:

• Esterase D (ES-D) is a polymorphic enzyme found in human red blood cells.
• Understanding the genetic variation of ES-D is important for population genetics studies and forensic applications.

Purpose of the Study:

• To determine the phenotypes and gene frequencies of esterase D in the Assamese population.
• To establish baseline genetic data for this specific ethnic group.

Main Methods:

• A simplified and rapid cellulose acetate electrophoresis technique was employed.
• Phenotyping of esterase D was performed on samples from the Assamese population.

Main Results:

• The gene frequencies for esterase D types were calculated.
• The frequency of Es D(1) was found to be 0.7263.
• The frequency of Es D(2) was determined to be 0.2737.

Conclusions:

• The Assamese population exhibits specific esterase D gene frequencies.
• The employed electrophoresis method is efficient for population screening.