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Mitochondrial disease: a pulmonary and critical-care medicine perspective
A S Clay1, M Behnia, K K Brown
1Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Chest
|August 15, 2001
Abstract:
The clinical spectrum of mitochondrial diseases has expanded dramatically in the last decade. Abnormalities of mitochondrial function are now thought to participate in a number of common adult diseases, ranging from exercise intolerance to aging. This review outlines the common presentations of mitochondrial disease in ICUs and in the outpatient setting and discusses current diagnostic and therapeutic options as they pertain to the pulmonary and critical-care physician.