Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Esterase D: some population and formal genetical data.

C Rittner, G Müller

    Human Heredity
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Responsible dealing with sexuality. Recommendations in a clinical institution].

    Der Nervenarzt·2011
    Same author

    Hepatitis B surface antigen presentation and HLA-DRB1*- lessons from twins and peptide binding studies.

    Clinical and experimental immunology·2005
    Same author

    [Ethical decision-making at the end of life--knowledge and attitudes of medical students].

    Deutsche medizinische Wochenschrift (1946)·2004
    Same author

    Differential regulation of interleukin-10 production by genetic and environmental factors--a twin study.

    Genes and immunity·2002
    Same author

    The human complement C9 gene: structural analysis of the 5' gene region and genetic polymorphism studies.

    European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics·2002
    Same author

    Rapid detection of the ERV-K(C4) retroviral insertion reveals further structural polymorphism of the complement C4 genes in old world primates.

    Experimental and clinical immunogenetics·2001
    Same journal

    Comparative profiles of pediatric Mendeliome: A Single-Centre 572-Whole-Exome Sequencing Study in Xinjiang.

    Human heredity·2026
    Same journal

    Erratum.

    Human heredity·2026
    Same journal

    Exploratory Analysis of HMGB1 Genetic Variants and Their Potential Association with Lung Cancer Susceptibility and Chemotherapy Response in a Chinese Population.

    Human heredity·2025
    Same journal

    Weighted Burden Analysis of Rare Genetic Variants Identifies Novel Genes with Effects on BMI.

    Human heredity·2025
    Same journal

    Generalized Stable Population and Agent-Based Models of Phenotypic Transmission in Human Populations, with an Application to Body Size.

    Human heredity·2025
    Same journal

    Proteinase-activated receptor 2 (PAR-2) expression and F2RL1 genetic variants are associated with asthma: a case-control study in the Chinese population.

    Human heredity·2025
    See all related articles

    Esterase D (EsD) allele frequencies were analyzed in healthy donors and families. Results align with Caucasian population data, with a rare EsD3 variant observed and successfully transmitted across generations.

    Area of Science:

    • Human genetics
    • Population genetics
    • Biochemistry

    Background:

    • Esterase D (EsD) is a polymorphic enzyme relevant in human genetic studies.
    • Understanding EsD allele frequencies is crucial for population genetics and forensic science.

    Purpose of the Study:

    • To determine Esterase D (EsD) allele frequencies in a Caucasian population.
    • To investigate the inheritance patterns of EsD variants within families.

    Main Methods:

    • Genotyping of 562 healthy blood donors for EsD.
    • Analysis of 65 families (149 offspring) for EsD segregation.
    • Comparison of observed allele frequencies with existing population data.

    Main Results:

    • Observed EsD allele frequencies are consistent with other Caucasian populations.

    Related Experiment Videos

  • The rare EsD3 variant was identified in one blood donor and transmitted to his offspring.
  • Segregation ratios within families did not deviate from expected Mendelian patterns.

    • Conclusions:

    • The EsD genetic system exhibits expected frequencies and inheritance in this Caucasian cohort.
    • The findings support the utility of EsD typing in genetic and forensic applications.
    • Further studies can build upon these established population frequencies.