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[A prospective study of posttransfusion hepatitis B virus infection]
1Department of Transfusion, Xiangya Hospital of Hunan Medical University, Changsha 410008, China.
Objective:
To understand the status of HBV posttransfusion infection after blood HBsAg screening of the blood donors.
Methods:
Serum samples of blood recipients and donors were detected for HBV-M and HBV DNA by ELISA technique and polymerase chain reaction respectively.
Results:
There were 326 sera positive for HBV-M and 57 for HBV DNA in 583 blood donors' sera. 39 sera were positive for HBV-M and 23 positive for HBV-DNA in 136 sera of blood recipients, the positive seroconversion rates were 28.68% and 16.9% respectively.
Conclusions:
There is high incidence of HBV infection in blood donors though they have been screened for HBsAg. The posttransfusion HBV infections are still occurring, therefore, the blood donors should be strictly tested for HBV-M. If conditions are possible, the HBV DNA had better been screened.