[Childhood cancers in the Netherlands (1989-1997)]

In a recent report by the Society of Integral Cancer Centres in the Netherlands, attention was devoted to the incidence of cancer in children and the mortality arising from this. In recent years the growing diagnostic and therapeutic possibilities have changed the perspective of childhood cancer enormously. Based on a careful classification and clinical staging, national and international investigations have resulted in new and successful therapeutical strategies. Overall prognoses of childhood cancer have improved dramatically from a 5-year survival rate in the 1960s and 1970s of less than 30%, to an 8-year survival rate of more than 70% between 1989 and 1997. However, this success means that more investigations into the long-term effects of childhood cancer and its treatment are needed. In a study at the Amsterdam University Hospital, 700 adult survivors of childhood cancer were reinvestigated of whom over 75% experienced one or more clinically relevant long-term effects. A continuous survey for long-term effects is needed for the development of new therapeutic strategies, which allow children treated for cancer to develop with the same possibilities in life as their healthy peers.