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[About side effects of platinum drugs]
1Wydział Chemii Uniwersytetu Wrocławskiego we Wrocławiu.
Postepy Higieny I Medycyny Doswiadczalnej
|August 17, 2001
Abstract:
The work presents current view about toxic effects of platinum anticancer drugs. In the first part, the toxic effects of cisplatin as nephrotoxicity, ototoxicity, myelosuppression, anaphylactic-like reactions, neurotoxicity and gastrotoxicity are presented. The second part describes mechanisms of nephrotoxicity of cisplatin. In the third part, the toxicity of carboplatin and iproplatin are reviewed.