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Amebiasis in Japanese homosexual men with human immunodeficiency virus infection

S Mitarai1, H Nagai, K Satoh

  • 1Department of Respiratory Medicine, National Tokyo Hospital, Kiyose.

Internal Medicine (Tokyo, Japan)
|August 17, 2001
PubMed

Insights

Invasive amebiasis can cause severe illness in human immunodeficiency virus (HIV)-positive men, particularly homosexual individuals. Early diagnosis and treatment are crucial to prevent complications like perforation and death.

Area of Science:

  • Infectious Diseases
  • Hepatology
  • Gastroenterology

Background:

  • Amebiasis, caused by Entamoeba histolytica, is an opportunistic infection.
  • Human immunodeficiency virus (HIV) infection can increase susceptibility to opportunistic pathogens.
  • Invasive amebiasis is rare, even in immunocompromised individuals.

Observation:

  • Six human immunodeficiency virus (HIV)-positive male patients presented with amebiasis.
  • Five patients were homosexual, and one was suspected homosexual.
  • Clinical presentations included liver abscess (3 cases) and colitis (5 cases).

Findings:

  • Patients with liver abscess had less abdominal pain but more diarrhea.
  • Drainage therapy led to rapid improvement in liver abscess cases.
  • Two patients with invasive colitis died due to perforation, possibly from delayed diagnosis.

Implications:

  • Invasive amebiasis may be more prevalent in Japanese homosexual men with HIV.
  • Prompt diagnosis and intervention are critical for managing invasive amebiasis in this population.
  • This highlights the importance of considering amebiasis in HIV-positive individuals with gastrointestinal or liver symptoms.

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