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Updated: Jul 28, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Fungal ring infiltrates in disposable contact lens wearers
A L Salierno1, M H Goldstein, W T Driebe
1Department of Ophthalmology, University of Florida, Gainesville, USA.
Purpose:
To report two cases of ring infiltrates in disposable contact lens wearers resembling Acanthamoeba keratitis but later identified as fungus.
Methods:
We report two patients with histories of disposable soft contact lens use, who, on initial presentation, were found to have corneal ring infiltrates and were treated for presumed Acanthamoeba keratitis. Microbiological studies, which included Gram stain and Gomori methenamine silver stain, as well as blood agar, chocolate agar, thioglycolate broth, Sabouraud agar, nonnutrient agar with Escherichia coli overlay, and Lowenstein-Jensen plates, were performed.
Results:
Microbiological studies revealed fungi in both cases.
Conclusions:
Fungal keratitis is an uncommon complication of disposable soft contact lens use, but it should be considered in the differential diagnosis of corneal ring infiltrates.
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