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Updated: Oct 5, 2026

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Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
An orthotopic xenograft model of human nonseminomatous germ cell tumour
M L Douglas1, K J Boucaut, T M Antalis
1Department of Surgery, Princess Alexandra Hospital, University of Queensland, Brisbane, Queensland 4102, Australia.
British Journal of Cancer
|August 17, 2001
Abstract:
We have established the first example of an orthotopic xenograft model of human nonseminomatous germ cell tumour (NSGCT). This reproducible model exhibits many clinically relevant features including metastases to the retroperitoneal lymph nodes and lungs, making it an ideal tool for research into the development and progression of testicular germ cell tumours.

