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Zinc and cognitive development.

S Bhatnagar1, S Taneja

  • 1All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India. shinjini_bhatnagar@rediffmail.com

The British Journal of Nutrition
|August 18, 2001
PubMed
Summary
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Zinc deficiency can impair cognitive development, affecting attention and behavior. Supplementation shows promise for improving motor skills and activity in infants and toddlers, though more research is needed.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Nutritional Science

Background:

  • Cognition involves perception, thinking, memory, learning, and attention.
  • Zinc is crucial for brain development, including neurogenesis and synaptogenesis.
  • Zinc deficiency may negatively impact cognitive functions and behavior.

Purpose of the Study:

  • To review the impact of zinc deficiency on cognitive development.
  • To explore the mechanisms underlying zinc's role in brain function.
  • To summarize evidence from animal and human studies on zinc and cognition.

Main Methods:

  • Literature review of animal and human studies.
  • Analysis of research on zinc's biochemical roles in the brain.
  • Examination of studies on zinc supplementation and cognitive outcomes.

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Main Results:

  • Animal studies show zinc deficiency impairs cognitive development and behavior.
  • Human studies indicate low maternal zinc intake affects infant attention and motor skills.
  • Zinc supplementation improved motor development and activity in infants and toddlers.

Conclusions:

  • Zinc is essential for optimal cognitive development.
  • Further research is needed to clarify mechanisms, critical periods, and long-term effects.
  • Zinc supplementation may benefit cognitive and motor functions in specific populations.