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The British version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ)
J Nugent1, N Ruperto, J Grainger
1Institute of Child Health, University College, London, United Kingdom.
Insights
The British versions of the Childhood Health Assessment Questionnaire (CHAQ) and Child Health Questionnaire (CHQ) are reliable tools for assessing children with juvenile idiopathic arthritis (JIA). These instruments effectively measure functional ability and well-being in pediatric patients.
Area of Science:
- Pediatric Rheumatology
- Health Outcomes Research
- Cross-Cultural Adaptation
Background:
- Juvenile idiopathic arthritis (JIA) impacts children's functional ability and well-being.
- Validated health-related quality of life instruments are crucial for assessing JIA patients.
- Existing instruments require adaptation for specific cultural and linguistic contexts, such as British English.
Purpose of the Study:
- To cross-culturally adapt and validate the parent's versions of the Childhood Health Assessment Questionnaire (CHAQ) and Child Health Questionnaire (CHQ) into British English.
- To assess the reliability and validity of the adapted CHAQ and CHQ for use in children with JIA.
- To evaluate the instruments' ability to discriminate between JIA subtypes and healthy children.
Main Methods:
- Cross-cultural adaptation and validation of the parent's versions of the CHAQ and CHQ into British English.
- Enrollment of 440 subjects: 219 children with JIA (various subtypes) and 221 healthy children.
- Statistical analysis to assess reliability, validity, and discriminative ability of the adapted instruments.
Main Results:
- The British versions of the CHAQ and CHQ demonstrated clinical discrimination between healthy children and those with JIA.
- JIA subtypes (systemic, polyarticular, extended oligoarticular) showed higher disability, pain, and lower well-being compared to healthy peers.
- The CHQ indicated lower physical and psychosocial well-being in JIA patients compared to healthy controls.
Conclusions:
- The British versions of the CHAQ and CHQ are reliable and valid instruments for assessing children with JIA.
- These tools provide a comprehensive assessment of functional, physical, and psychosocial status in pediatric patients with JIA.
- The validated instruments support improved clinical management and research for JIA in the UK population.
Abstract:
We report herein the results of the cross-cultural adaptation and validation into the British language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. A total of 440 subjects were enrolled: 219 patients with JIA (17% systemic onset, 41% polyarticular onset, 33% extended oligoarticular subtype, and 9% persistent oligoarticular subtype) and 221 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers. In conclusion the British version of the CHAQ-CHQ is a reliable, and valid tool for the functional, physical and psychosocial assessment of children with JIA.