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Panniculitis. Part II. Mostly lobular panniculitis.

L Requena1, E Sánchez Yus

  • 1Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

Journal of the American Academy of Dermatology
|August 21, 2001
PubMed
Summary
This summary is machine-generated.

This review details clinicopathologic features of lobular panniculitides, including erythema induratum and disorders without vasculitis. It covers inflammatory, neoplastic, and other causes of subcutaneous fat issues.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Panniculitis encompasses inflammatory conditions affecting subcutaneous fat.
  • Lobular panniculitides are a diverse group with varied etiologies and presentations.

Purpose of the Study:

  • To summarize the clinicopathologic features of mostly lobular panniculitides.
  • To familiarize participants with pathogenesis, clinical manifestations, histopathology, and treatment of frequent lobular panniculitis variants.

Main Methods:

  • Review of clinicopathologic features of lobular panniculitides.
  • Categorization based on presence or absence of vasculitis.
  • Inclusion of associated conditions and differential diagnoses.

Main Results:

  • Erythema induratum of Bazin is the most common lobular panniculitis with vasculitis.
  • Lobular panniculitides without vasculitis include sclerosing panniculitis, calciphylaxis, oxalosis, and inflammatory diseases with crystals.
  • Other associations include connective tissue diseases, pancreatic diseases, alpha(1)-antitrypsin deficiency, infections, trauma, factitial causes, lipoatrophy, lipodystrophy, and cytophagic histiocytic panniculitis.

Conclusions:

  • Lobular panniculitides present a wide spectrum of clinicopathologic findings.
  • Accurate diagnosis requires integration of clinical, histopathologic, and etiological factors.
  • Understanding these variants is crucial for appropriate patient management.