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Radiation therapy for Bowen's disease: lessons for lesions of the lower extremity
M T Dupree1, R A Kiteley, K Weismantle
1Radiation Oncology Division, Dermatology Department, University of California, San Diego, CA 92134, USA.
Objective:
A retrospective outcomes review of radiotherapy for Bowen's disease was performed to analyze all patients treated with radiation therapy between 1993 and 1997 at the Naval Medical Center, San Diego.
Methods:
Eleven patients with 16 lesions were treated with a median time-dose-fractionation value of 105 (range, 93-108).
Results:
All 11 patients were without evidence of disease within 1 to 2 months of completing treatment. Four of the 16 lesions (25%) were unhealed at time of last follow-up; the remainder healed with good cosmetic result. All unhealed lesions were on the lower extremity. Median follow-up was 27.5 months (range, 9-57 months).
Conclusion:
Radiation remains a good therapeutic option in selected patients with Bowen's disease, but caution should be exercised before selection of patients with lesions in potentially poor healing areas, such as the lower extremity.