Related Experiment Videos
Atypical focal non-neoplastic brain changes in neurofibromatosis type 1: mass effect and contrast enhancement
R Raininko1, L Thelin, O Eeg-Olofsson
1Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Sweden. raili.raininko@radiol.uu.se
Neuroradiology
|August 22, 2001
Abstract:
Children and young adults with neurofibromatosis type 1 often have small high-signal foci on T2-weighted images of the brain. We describe follow-up of two patients in whom one of the foci had atypical features, commonly regarded as signs of a neoplasm. In the first, one lesion showed temporary contrast enhancement and decreasing mass effect. The second developed an expanding lesion that increased minimally in size over 4.5 year's follow-up. The borderline between neoplastic and non-neoplastic lesions seems to be indistinct.