Related Experiment Video
Updated: Oct 5, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
Published on: October 14, 2021
A successful clonazepam treatment without tolerance in a patient with spontaneous oral dyskinesia
T Fukasawa1, M Takahashi, K Otani
1Department of Neuropsychiatry, Yamagata University School of Medicine, Japan.
Abstract:
There has been few reports on the effective treatment for SOD, which is phenomenologically similar to TD. A 66-year-old female with SOD was successfully treated by CNZ 2 mg/day. Even after one year of continuous treatment, tolerance, which is the major problem in the CNZ treatment for TD, did not develop. This report suggests that CNZ is effective at least for some patients with SOD.
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