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Caseous lymphadenitis in small ruminants.

L H Williamson1

  • 1Department of Large Animal Medicine, University of Georgia, College of Veterinary Medicine, Athens, Georgia, USA. Lwilliam@vet.uga.edu

The Veterinary Clinics of North America. Food Animal Practice
|August 23, 2001
PubMed
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Caseous lymphadenitis, a contagious bacterial disease in sheep and goats caused by Corynebacterium pseudotuberculosis, presents challenges in eradication due to environmental persistence and difficulty in detecting subclinical cases.

Area of Science:

  • Veterinary Medicine
  • Bacteriology
  • Animal Science

Background:

  • Caseous lymphadenitis (CL) is a significant contagious bacterial disease affecting small ruminants.
  • Caused by Corynebacterium pseudotuberculosis, CL leads to abscess formation in lymph nodes and internal organs.
  • The disease poses economic challenges to the sheep and goat industries.

Purpose of the Study:

  • To provide a comprehensive overview of caseous lymphadenitis in sheep and goats.
  • To highlight the causative agent, clinical manifestations, and economic impact of CL.
  • To discuss the difficulties in eradicating CL from affected herds and flocks.

Main Methods:

  • Review of existing literature on caseous lymphadenitis.
  • Analysis of the characteristics of Corynebacterium pseudotuberculosis.

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  • Examination of the epidemiological factors contributing to CL persistence.

    • Main Results:

    • CL is characterized by abscess formation in superficial and internal lymph nodes and organs.
    • Corynebacterium pseudotuberculosis is the primary etiological agent.
    • Eradication is hindered by poor therapeutic response, environmental persistence, and subclinical infections.

    Conclusions:

    • Caseous lymphadenitis is an economically impactful disease in small ruminants.
    • Effective control strategies are needed to manage CL due to its persistence and transmission dynamics.
    • Further research into diagnostics and therapeutics is crucial for combating CL.