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Updated: Oct 5, 2026

Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV
Published on: January 19, 2024
Innocuous mechanical stimulation of the neck and alterations in heart-rate variability in healthy young adults
1College of Medical Technology, Kyoto University, Japan. budgell@itan.kyoto-u.ac.jp
Abstract:
The present study examined the effects of cervical spinal manipulation, a widely applied form of physical therapy, which involves innocuous mechanical stimulation, on heart rate and heart-rate variability, in a cohort of healthy young adults. Using a cross-over treatment design, with a one-week washout period and, in contrast to a sham procedure, the authentic manipulation produced significant alterations in both heart rate and measures of heart-rate variability calculated from power spectrum analysis. In particular, there was an increase in the ratio of low-frequency (LF)-to-high-frequency (HF) components of the power spectrum of heart-rate variability, which may reflect a shift in balance between sympathetic and parasympathetic output to the heart.
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