Related Experiment Videos
REST acts through multiple deacetylase complexes
E C Griffith1, C W Cowan, M E Greenberg
1Division of Neuroscience, Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Neuron
|August 23, 2001
Abstract:
The RE1 binding silencer protein REST represses neuronal-specific gene expression in nonneuronal cell types. In this issue of Neuron, Ballas et al. show that REST inhibits gene expression via the recruitment of multiple histone deacetylase complexes.