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Motile organelles: the importance of specific tubulin isoforms
1Department of Genetics, Washington University School of Medicine, 660 s. Euclid, St. Louis, Missouri 63110, USA. dutcher@genetics.wuustl.edu
Current Biology : CB
|August 23, 2001
Abstract:
The requirements for building flagellar axonemes and centrioles are beginning to be uncovered. The carboxyl terminus of a specific beta tubulin isoform plays an important role in forming the '9 + 2' structure of the axoneme; delta tubulin plays an essential role in forming the triplet microtubules of centrioles and basal bodies.