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Catabolic and anabolic signals in bone: therapeutic implications
1Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Current Opinion in Clinical Nutrition and Metabolic Care
|August 23, 2001
Abstract:
Bone remodelling accounts for the continuous renewal of the adult skeleton, and its disturbances constitute the pathophysiological basis of most skeletal disorders. Recently identified bone signalling pathways explain the action of known therapeutic agents and provide targets for new developments in the management of bone diseases.