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Updated: Oct 4, 2026

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
Published on: July 4, 2018
[Microecological system and its importance in evaluation of the effectiveness of biologically active supplements and
Abstract:
A possibility to estimate a quality of bioactive supplements and probiotical foods by their influence on microecological system of a gastrointestinal tract are exhibited as a result of multiyear research. The consist and biological activity of micropopulations, including the normalization of level of protective intestinal microflora, the increasing their antibiosis activity, the elimination of potentially pathogenic microorganisms, the excretion of volatile phenols and indican with urine, the content of volatile fatty acids, enzymes, secretory immunoglobulins in feces, destruction in vitro cholic acid and cholesterol etc., are tested as indicators. The reasoned supposal is advanced that the wide spread of disbacteriosis is connected not only with changing of defence mechanisms (reactions) of macroorganism, but also with accumulation of pathogenic features in microorganisms by action of environmental factors.
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