Related Experiment Videos
Synthesis and properties of 18F-labeled potential myocardial blood flow tracers
1Department of Chemistry, Case Western Reserve University, University Hospital of Cleveland, Cleveland, OH 44106, USA. ars5@po.cwru.edu
Nuclear Medicine and Biology
|August 24, 2001
Abstract:
PET centers without particle accelerators make clinical PET widely available at reduced cost. For myocardial perfusion tracers, these satellite PET centers are limited to generator- produced 82Rb(+) and 62Cu[PTSM]. Their limitations motivate a search for transportable alternatives. In search of new tracers we have synthesized several 18F-labeled amines and quaternary ammonium salts. Among them, 4-[18F]fluorotri-N-methylanilinium ([18F]FTMA) has flow-tracing properties. The compound is functional, but has properties that justify a continued search.