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Updated: Oct 4, 2026
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[A case of IgG4-lambda type monoclonal immunoglobulin that interfered with determinations for albumin, direct
Abstract:
We report a human IgG4-lambda type M-protein that reacts with reagents of albumin, direct bilirubin and iron. Blood chemistry findings by an automated analyzer were: total protein 8.8 g/dl; albumin(ALB) 9.2 g/dl; direct bilirubin(D-Bil) -6.2 mg/dl; and iron(Fe) 25 micrograms/dl. The white precipitates were formed by the interaction of the patient's serum with reagents of ALB, D-Bil, and Fe. Immunofixation electrophoresis revealed that these precipitates were the IgG4-lambda type M-protein. Western blotting analysis showed that the IgG4 molecules were composed of two 55 kDa gamma 4 chains and two 24 kDa lambda chains.
