[Thrombolysis in cerebral ischemia. An overview]
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Updated: Oct 4, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
P D Schellinger1, J Fiebach, P A Ringleb
1Neurologische Klinik des Universitätsklinikum Heidelberg, im Neuenheimer Feld 400, Kopfklinik, 69120 Heidelberg. Peter_Schellinger@med.uni-heidelberg.de
Abstract:
Thrombolytic therapy for acute ischemic stroke within the 3-h time window has been approved. In the US, where FDA approval has existed for about 4 years, less than 2% of stroke patients presently receive thrombolytic therapy. This review illustrates all completed trials of intravenous and intra-arterial thrombolytic therapy for carotid artery and vertebrobasilar artery stroke and includes recommendations for therapy, diagnostic procedures and their effect on patient selection, meta-analyses, phase IV trials, and cost efficacy analyses.
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