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Updated: Aug 6, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
[Pathogenesis of disturbances of the hemostatic system in neonates]
Insights
Neonatal hemostasis and erythron system disturbances are linked to maternal extragenital pathologies. Specific interventions are developed for infants with diabetic fetopathy or born to mothers with neurocirculatory asthenia.
Area of Science:
- Neonatal physiology
- Hematology
- Pathophysiology
Context:
- Maternal extragenital pathologies significantly impact neonatal health.
- Understanding neonatal hemostasis and erythron system is crucial.
Purpose:
- To elucidate the pathogenetic mechanisms of hemostasis and erythron system disturbances in neonates born to mothers with extragenital pathologies.
- To identify specific risk factors and clinical presentations associated with these disturbances.
Summary:
- Neonates born to mothers with extragenital pathologies exhibit significant clotting and erythron system changes.
- Vascular permeability disorders and metabolic abnormalities are also observed, particularly in infants with diabetic fetopathy or born to mothers with neurocirculatory asthenia.
- These findings highlight complex interconnections between maternal health and neonatal development.
Impact:
- The study results facilitated the development of targeted curative and prophylactic measures for affected neonates.
- This research contributes to improved neonatal care strategies for high-risk pregnancies.
- Enhanced understanding of neonatal pathophysiology can lead to better clinical outcomes.
Abstract:
Described in the paper are chief pathogenetic mechanisms of development of disturbances in the hemostasis system in neonates born to mothers presenting with extragenital pathologies. Marked clotting changes were noted together with those in the system of the erythron. Recordable in the above infants were also vascular permeability disorders, abnormalities of metabolism. These changes were especially manifest in those children presenting with diabetic fetopathy and in babies born to mothers with neurocirculatory asthenia. The results secured permitted the development of the system of curative-and-prophylactic measures to be instituted in the above infants.
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