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Updated: Aug 7, 2026

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Published on: March 14, 2017
Alcoholic liver cirrhosis complicated with torsade de pointes during plasma exchange and hemodiafiltration
H Nakasone1, R Sugama, H Sakugawa
1First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Abstract:
A 36-year-old man with severe alcoholic hepatitis was treated with plasma exchange combined with hemodiafiltration to remove endotoxins and inflammatory cytokines. During the treatment, he had critical arrhythmia (torsade de pointes [TdP]). His laboratory data showed hypomagnesemia, which was suspected to be responsible for the development of TdP. Patients with alcoholic liver disease tend to have hypomagnesemia and Q-T interval prolongation. Furthermore, hemodiafiltration may cause hypomagnesemia. Careful observation for electrolytic imbalance is necessary when clinicians treat patients with alcoholic liver failure with a liver support system.
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