Related Experiment Video
Updated: Aug 12, 2026

Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids
Published on: January 26, 2012
Evolution of catabolic pathways and metabolic versatility in Pseudomonas stutzeri OX1
P Barbieri1, F L Arenghi, G Bertoni
1Dipartimento di Genetica e di Biologia dei Microorganismi, Università degli Studi di Milano, Italy. Paola.Barbieri@unimi.it
Abstract:
Pseudomonas stutzeri OX1 is able to degrade toluene and ortho-xylene via the direct oxygenation of the aromatic ring. The genetic studies carried out suggest that the genes coding for the monooxygenase involved in the early steps of this catabolic route have been acquired by gene transfer. P stutzeri OX1 is also potentially able to utilize meta- and para-xylene as growth substrates. These two isomers are metabolized through a different pathway (TOL pathway). Both catabolic routes can be activated or inactivated by means of genomic rearrangements. The relevance of such recombination mechanisms in the evolution and the adaptability of P. stutzeri is discussed.
More Related Videos
Related Concept Videos
Microbial Nutrition
Other Glycolytic Pathways
Lipid Catabolism
Biosynthesis in Bacteria
Evolution of New Traits in Microbes
Deep Sea Microbial Ecology

