Related Experiment Video
Updated: Apr 4, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
New bromoditerpenes from the red alga Sphaerococcus coronopifolius
S Etahiri1, V Bultel-Poncé, C Caux
1Laboratoire de Biochimie Marine, Faculté des Sciences, Université Chouaib Doukkali, BP 20, El Jadida, Maroc.
Abstract:
The organic extract of the red alga Sphaerococcus coronopifolius, collected along the Atlantic coast of Morocco, was tested for biological activities and exhibited antibiotic and antimalarial activities. Two new bromoditerpenes have been isolated from S. coronopifolius, sphaerolabdadiene-3,14-diol (1) and bromosphaerone (2), along with the known compounds 12S-hydroxybromosphaerodiol (3) and sphaerococcenol A (4). Bromosphaerone and 12S-hydroxybromosphaerodiol showed antibacterial activity against the Gram-positive bacterium species Staphylococcus aureus with a minimum inhibitory concentration of 0.104 and 0.146 microM, respectively. Sphaerococcenol A (4) was responsible for the antimalarial activity of the extract, against the chloroquine resistant Plasmodium falsciparum FCB1 strains with an IC(50) of 1 microM. Their structures have been assigned using 1 and 2 D NMR and HRMS.
More Related Videos
09:49Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
08:18Non-Aqueous Isolation and Enrichment of Glandular Capitate Stalked and Sessile Trichomes from Cannabis sativa
Published on: May 12, 2023
Related Concept Videos
Halogenation of Alkenes
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Formation of Halohydrin from Alkenes
Overview of Algae
Red Algae
Green Algae
Other Algae