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Updated: Aug 15, 2026

Sheathless Capillary Electrophoresis–Mass Spectrometry for Metabolic Profiling of Biological Samples
Published on: October 1, 2016
Ionization of dichlorophenols for their analysis by capillary electrophoresis-mass spectrometry
1Special Division of Green Life Technology, AIST Kansai National Institute of Advanced Science and Technology, Ikeda, Osaka, Japan. takeda-s@aist.go.jp
Abstract:
In order to develop an advanced analytical method using capillary electrophoresis (CE) for non-volatile environmental pollutants such as endocrine disruptors, combination with mass spectrometry (MS) is necessary for their identification. We chose dichlorophenols (DCPs) as test samples because one of their isomers, 2,4-DCP, is suspected to have endocrine disrupting effects. A preliminary study on their separation by CE-MS was performed using a laboratory-made electrospray ionization (ESI) interface. For the effective ionization of 2,4-DCP at the
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