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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Published on: March 12, 2015

Lack of expression of the dense granule protein GRA5 does not affect the development of Toxoplasma tachyzoites

C Mercier1, B Rauscher, L Lecordier

  • 1PEGM CNRS FRE 2383, Bâtiment CERMO, Université Joseph Fourier, 38041 cedex 09, Grenoble, France.

Molecular and Biochemical Parasitology
|August 28, 2001
PubMed
Abstract

No abstract available in PubMed .

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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

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