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Related Experiment Videos

[Cardiovascular pathology in dermatomyositis].

A P Solov'eva, V S Moiseev, V V Chel'tsov

    Kardiologiia
    |May 1, 1975
    PubMed
    Summary
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    Cardiovascular pathology is common in dermatomyositis patients, often presenting as myocardial lesions and ECG changes. Some cardiac issues may stem from corticosteroid therapy or severe muscle involvement.

    Area of Science:

    • Cardiology
    • Rheumatology
    • Internal Medicine

    Context:

    • Dermatomyositis is an idiopathic inflammatory myopathy.
    • Cardiovascular involvement is a known, though not fully understood, complication.

    Purpose:

    • To investigate the prevalence and nature of cardiovascular pathology in dermatomyositis patients.
    • To explore the relationship between cardiac findings, disease activity, and corticosteroid therapy.

    Summary:

    • 77 out of 110 dermatomyositis patients exhibited cardiovascular pathology, with myocardial lesions (often non-specific ECG changes) being most frequent.
    • Cardiac insufficiency and arrhythmias occurred less often, primarily during disease flares. Corticosteroid therapy induced myocardial dystrophy in 18 patients.
    • Central hemodynamics showed a hyperkinetic state in patients with severe muscle involvement, and bulbar conjunctiva angioscopy revealed persistent vascular changes.

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    Impact:

    • Highlights the significant burden of cardiac complications in dermatomyositis.
    • Suggests a need for routine cardiovascular monitoring in these patients.
    • Provides insights into potential mechanisms of cardiac involvement, including steroid effects and disease severity.