[Progress in neurosciences: initiatives within the framework of the program "Brain Decade (1990-2000)"]

Area of Science:

• Neurology
• Neuroscience
• Medical Research

Context:

• Research conducted over the past decade at the Research Institute of Neurology, Russian Academy of Medical Sciences.
• Focus on cerebrovascular diseases, degenerative and demyelinating diseases of the nervous system.

Purpose:

• To present key scientific and practical outcomes in neurological research.
• To highlight advancements in diagnostics, disease criteria, and treatment strategies for various neurological disorders.

Summary:

• Development of national criteria for brain death.
• New methods for diagnosing prion diseases and evaluating neuronal apoptosis.
• Discovery of new hereditary nervous system diseases with direct DNA diagnosis.
• Establishment of a national family register and DNA data bank for monogenous hereditary diseases.
• Indications for surgical interventions (cerebral bypass) and therapeutic procedures (programmable plasmapheresis).
• Development of rehabilitative programs and identification of biomarkers for atherosclerotic plaque.

Impact:

• Enhanced diagnostic capabilities for complex neurological conditions.
• Improved understanding and management of cerebrovascular and autoimmune neurological diseases.
• Foundation for personalized medicine through genetic diagnosis and family registries.
• Advancements in neurorehabilitation and prediction of neurological events.