Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mycotic encephalitis in weanling rats.

J P Rapp, J T McGrath

    Laboratory Animal Science
    |August 1, 1975
    PubMed
    Summary

    An outbreak of mycotic encephalitis, a fungal infection of the brain, occurred in young rats. This study identified phycomycosis (mucormycosis) as the cause in affected rodents.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Two linked blood pressure quantitative trait loci on chromosome 10 defined by dahl rat congenic strains.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    High-resolution mapping of the blood pressure QTL on chromosome 7 using Dahl rat congenic strains.

    Genomics·2001
    Same author

    Multiple blood pressure QTL on rat chromosome 1 defined by Dahl rat congenic strains.

    Physiological genomics·2001
    Same author

    Localization of a blood pressure QTL on rat chromosome 1 using Dahl rat congenic strains.

    Physiological genomics·2000
    Same author

    Blood pressure QTL that differentiate Dahl salt-sensitive and spontaneously hypertensive rats.

    Physiological genomics·2000
    Same author

    Genetic analysis of inherited hypertension in the rat.

    Physiological reviews·2000

    Area of Science:

    • Veterinary Pathology
    • Mycology
    • Rodent Disease Outbreaks

    Background:

    • Mycotic encephalitis is a serious fungal infection affecting the central nervous system.
    • Outbreaks in animal models require prompt identification and characterization.
    • Phycomycosis, also known as mucormycosis, is a group of fungal infections caused by fungi in the order Mucorales.

    Purpose of the Study:

    • To report and characterize an outbreak of mycotic encephalitis in laboratory rats.
    • To identify the causative fungal agent and its pathological presentation.

    Main Methods:

    • Histopathological examination of brain tissue from affected rats.
    • Microscopic analysis to identify fungal elements and characteristic lesions.
    • Epidemiological data collection on affected animals.

    Main Results:

    • Eight out of 170 young rats (15-31 days old) developed mycotic encephalitis.
    • Histopathology confirmed the infection as phycomycosis (mucormycosis).
    • No evidence of fungal infection was found in other organs, indicating a primary brain infection.

    Conclusions:

    • Young rats are susceptible to mycotic encephalitis caused by phycomycosis.
    • This outbreak highlights the importance of considering fungal infections in rodent neurological disease.
    • Further investigation into the source and transmission of the outbreak is warranted.

    Related Experiment Videos