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Updated: Feb 28, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
[Minimally invasive surgery for breast cancer]
K Sawai1, H Nakajima, N Mizuta
1Dept. of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-Agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto 602-8566, Japan.
Minimally invasive breast cancer surgeries, including sentinel lymph node biopsy and endoscopy-assisted procedures, are improving patient outcomes in Japan. These advanced techniques offer less invasive options, enhancing the quality of life for breast cancer patients.
Area of Science:
- Oncology
- Surgical Oncology
- Minimally Invasive Surgery
Context:
- Breast conservation surgery is a standard minimally invasive approach for breast cancer in Japan.
- Emerging techniques include sentinel lymph node biopsy (SLNB), day surgery, and endoscopy-assisted surgery.
- SLNB aids in precise lymph node staging, enabling tailored treatment for early-stage breast cancer.
Purpose:
- To introduce and evaluate advanced minimally invasive surgical techniques for breast cancer treatment.
- To highlight the benefits of SLNB, day surgery, and endoscopy-assisted surgery in improving patient care.
- To demonstrate the feasibility of performing lymph node dissection and reconstruction via endoscopy.
Summary:
- Sentinel lymph node biopsy (SLNB) using dye or isotope injection allows accurate identification of metastatic lymph nodes.
- Node-negative T1N0 breast cancer patients can avoid complete lymph node dissection when SLN biopsy is negative.
- Endoscopy-assisted surgery enables gland removal and axillary dissection through a small incision, with options for immediate reconstruction.
Impact:
- These minimally invasive approaches reduce patient morbidity and improve the quality of life post-treatment.
- SLNB facilitates accurate staging and avoids unnecessary procedures for node-negative patients.
- Endoscopic techniques offer oncological safety with improved cosmesis and faster recovery.
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