Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physical excercise and thrombotic risk in the elderly.

M T Veríssimo1, A Aragäo, A Sousa

  • 1Serviço de Medicina I dos Hospitais da Universidade de Coimbra Laboratório de Hematologia Clínica dos Hospitais da Universidade de Coimbra.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|August 30, 2001
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Comparison of dalbavancin with standard of care in the management of infective endocarditis: efficacy, safety, and cost analysis" [International Journal of Infectious Diseases, Volume 138 (January 2024), Pages 41-45].

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

Precision Measurement of Neutrino Oscillation Parameters with 10 Years of Data from the NOvA Experiment.

Physical review letters·2026
Same author

Innovative minicircle DNA vector encoding pri-miR-375 silences E6 and E7 oncoproteins in HPV16-positive CaSki cells.

Gene·2025
Same author

Digital proficiency and educational needs of Portuguese radiation therapists.

Radiography (London, England : 1995)·2025
Same author

Addressing Critical Fungal Pathogens Under a One Health Perspective: Key Insights from the Portuguese Association of Medical Mycology.

Mycopathologia·2025
Same author

Knowledge and HIV-related stigma among Portuguese healthcare professionals: A cross-sectional analysis.

HIV medicine·2025

Regular physical exercise in the elderly significantly reduced thrombotic risk factors like fibrinogen, factor VII, and plasma viscosity. This suggests exercise can help lower cardiovascular event risk in older adults.

Area of Science:

  • Gerontology
  • Cardiovascular Health
  • Exercise Physiology

Background:

  • Aging is associated with increased thrombotic risk factors, including fibrinogen, factor VII, plasminogen activator inhibitor-1 (PAI-1), and plasma viscosity.
  • These age-related changes contribute to cardiovascular diseases, a leading cause of death in developed nations.
  • Physical exercise is a potential intervention to mitigate these thrombotic tendencies.

Purpose of the Study:

  • To evaluate the impact of a regular physical exercise program on key thrombotic risk factors in an elderly population.
  • Specifically assessed were changes in fibrinogen, factor VII, PAI-1, and plasma viscosity.
  • The study aimed to determine if exercise could counteract age-related increases in these cardiovascular risk markers.

Main Methods:

Related Experiment Videos

  • A randomized controlled trial involving 63 elderly participants (aged 65-94) was conducted.
  • The test group (n=31) engaged in 8 months of moderate-intensity exercise (60-80% heart rate reserve), three times weekly for 60 minutes.
  • The control group (n=32) maintained their usual activity levels. Blood samples were analyzed pre- and post-intervention.

Main Results:

  • The exercise group showed significant reductions in fibrinogen, factor VII, and plasma viscosity.
  • No significant changes were observed in PAI-1 levels within the exercise group.
  • The control group exhibited no significant alterations in any of the measured parameters.

Conclusions:

  • Consistent physical exercise effectively decreases thrombotic risk in the elderly.
  • These findings support the role of regular exercise in potentially reducing the incidence of cardiovascular events among older adults.
  • Exercise interventions may be a valuable strategy for improving cardiovascular health in aging populations.