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LISA: an intranet-based flexible database for protein crystallography project management
P W Haebel1, V L Arcus, E N Baker
1School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Acta Crystallographica. Section D, Biological Crystallography
|August 30, 2001
Summary
A new database, LISA, manages protein crystallography project data. This freely available tool helps track experiments from sequences to publications, improving laboratory efficiency.
Area of Science:
- Structural Biology
- Bioinformatics
- Computational Biology
Background:
- Increasing project volume in protein crystallography necessitates robust data management.
- Existing systems may lack flexibility or web accessibility for comprehensive project tracking.
Purpose of the Study:
- To develop a flexible, web-accessible database for managing protein crystallography projects.
- To centralize diverse project information, including experimental data and results.
Main Methods:
- Developed a database named LISA (Laboratory Information System for crystallography).
- Utilized open-source software: MySQL for database and PHP4 for web interface.
- Integrated data fields for sequences, expression, purification, crystallization, structure coordinates, and publications.
Main Results:
- LISA provides comprehensive tracking of protein structure determination projects.
- Database includes links to relevant bioinformatics servers and data processing tools.
- The software package is freely available to the scientific community.
Conclusions:
- LISA offers an effective solution for managing complex protein crystallography project data.
- Web accessibility and integrated tools enhance usability and data processing.
- The free availability promotes wider adoption and improved research management.