Lymphoid follicular pattern of the colon in adults

The clinical and radiographic findings of the colonic lymphoid follicular pattern in 37 adults aged 20-79 years were evaluated. An incidence of 13% was found on review of 100 consecutive double-contrast barium enemas. Usually, the presence of multiple 1-3 mm diam, uniform-size nodules is sufficiently characteristic to make a presumptive diagnosis on these radiographic criteria. The nodules are often not visible endoscopically. The clinical data suggest that that the lymphoid follicular pattern is usually of no clinical significance in adults. In most patients, its radiologic pattern can be distinguished from entities such as familial polyposis and early Crohn's disease, thus sparing the patient unnecessary further diagnostic evaluation.