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Updated: Aug 18, 2026

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
Published on: February 11, 2021
Application of the Malone antegrade continence enema principle in degenerative leiomyopathy
M Chitnis1, S Chowdhary, C Lazarus
1Eastern Cape Paediatric Surgery Service, East London, South Africa.
Abstract:
An 1-year-old boy with degenerative leiomyopathy (DL) presented with a volvulus of the transverse colon. After derotating the volvulus, we constructed a tube colostomy (TC) from the transverse colon. This TC has been used for the past 2 years by the patient for regular deflation of the colon and antegrade colonic enemas (ACE). We present this as a preliminary report of the use of the Malone ACE procedure in a patient with DL and review the relevant literature.
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