Related Experiment Video
Updated: Aug 12, 2026

Chromatin Immunoprecipitation (ChIP) using Drosophila tissue
Published on: March 23, 2012
Biased distribution of repetitive elements: a landmark for neo-Y chromosome evolution in Drosophila miranda
1Institut für Zoologie, Technische Universität Darmstadt, Darmstadt, Germany.
Abstract:
It is generally assumed that the sex chromosomes developed from a pair of homologs. Over evolution, the proto-Y chromosome, with a very short differential segment, matured in its final stage into a heterochromatic and, for the most part, genetically eroded Y chromosome. The constraints on the evolution of the proto-Y chromosome have been speculated upon since the sex chromosomes were discovered. Several models have been suggested. Drosophila miranda has proved to be a unique and potent model system to study Y-chromosome evolution. We use selected test genes distributed along the neo-Y chromosome as entry gates to analyze the molecular mechanisms involved in the process of Y-chromosome evolution. Here, we report our findings on the Krüppel gene (Kr), which is located distally on the neo-sex chromosome pair.
More Related Videos
Related Concept Videos
Position-effect Variegation
Polytene Chromosomes
Non-LTR Retrotransposons
Cis-regulatory Sequences
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Heterochromatin
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...

