Paracoccidioidomycosis with palpebral and conjunctival involvement

A case of pulmonary and lymphatic paracoccidioidomycosis followed by conjunctivo-palpebral involvement is studied in Sao Paulo (Brazil). The Brazilian literature is reviewed. The most frequent clinic forms of ocular lesions in natural infection are described. The small number of human cases observed is discussed. The severity and frequency of ocular lesions in experimental animals, intracardiacally inoculated with P. brasilensis cultures suggest haematogenic ocular dissemination of the fungus, which may occur in the septicemic stage of the human paracoccidioidomycosis.